12 مهر 1400
What is the best treatment for this patient with right thigh swelling and these findings?
1. Glucocorticoids
2. Androgen deprivation therapy
3. Anticoagulation
4. Chemotherapy
5. Bisphosphonates
2. Androgen deprivation therapy
3. Anticoagulation
4. Chemotherapy
5. Bisphosphonates
پاسخ صحیح:
Bisphosphonates
Therapy with bisphosphonates is the correct answer. The patient has Paget’s disease, which is a bone metabolism disorder characterized by abnormal bone remodeling with excessive focal bone resorption and formation. Lab studies may reveal elevated alkaline phosphate levels and x-ray films may reveal lytic lesions, cortical thickening, osteoporosis, sclerosis, and bone enlargement. Bisphosphonates may be useful in the management of Paget’s disease
